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Receiving Protein C Concentrate (Human) (Ceprotin)

Dear Patient,
Your health care provider has prescribed protein C concentrate to replace the protein C that you're missing in your body. This will help stop the occurrence of venous clots and blood clotting problems. The brand name of this medication is Ceprotin.

How you'll receive Ceprotin
You'll receive Ceprotin by I.V. injection every 6 to 12 hours until your clotting tests have stabilized.

What to do if you miss a dose
If you miss a dose, immediately contact your health care provider about setting up a new dosing schedule.

What to do about side effects
Notify your health care provider if you experience side effects to this medication.
Common: hypersensitivity or allergic reactions (rash and itching), lightheadedness.
Less common: low blood pressure, fever, restlessness, excessive sweating.

What you must know about other medications
It isn't known if this medication interacts with other medications. There's a risk of clotting problems if combined with oral anticoagulants or a tissue plasminogen activator. Tell all of your health care providers that you're on this medication so precautions can be taken if needed.

Special directions

  • This medication will help your body to stabilize the clotting process. You'll need frequent blood tests to check your response to the medication.
  • The medication will be given every 6 to 12 hours until your clotting has stabilized.
  • This medication is made from human blood, and because of this there's a risk of disease transmission. Every precaution has been taken to lower that risk, but you should be aware of the possibility.

Keep in mind

  • It isn't known if this medication could affect an unborn baby. If you're pregnant or wish to become pregnant, consult your health care provider.
  • It isn't known how this medication could affect a breastfed baby. If you're breastfeeding, discuss this with your health care provider.
  • Report signs of hypersensitivity or allergic reaction to the medication (which may include mouse protein or heparin). Signs of reaction include hives, generalized skin rash, itching, tightness in the chest, wheezing, and difficulty breathing. If these signs occur the infusion should be stopped immediately. Also report increased bleeding.

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