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Diuretics for Metabolic Syndrome

The National Institutes of Health has reported that, among patients with hypertension and metabolic syndrome, thiazide-type diuretics offer better protection against cardiovascular disease—including coronary artery disease, peripheral artery disease, heart failure, and stroke—and are as effective at lowering blood pressure as more popular and costly treatments involving ACE inhibitors, alpha blockers, and calcium channel blockers. The beneficial effects of diuretics were especially clear among black patients.
   People with metabolic syndrome have three or more risk factors for cardiovascular disease, including hypertension, low high-density lipoprotein levels, and diabetes or pre-diabetes (fasting blood glucose level of 100 mg/dl or higher).
   The data come from the latest findings of the ALLHAT study and appear in the January 28 issue of the Archives of Internal Medicine.


     
   

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