levofloxacin
Levaquin	Pharmaceutical company: Ortho-McNeil Pharmaceutical Co. www.ortho-mcneil.com

NEW INDICATION & DOSAGE
Treatment of complicated urinary tract infections caused by Escherichia coli, Klebsiella pneumoniae or Proteus mirabilis, and acute pyelonephritis caused by E. coli--
Adults: 750 mg/day P.O. or I.V. for 5 days.
ADJUST-A-DOSE:
For patients with renal impairment--for creatinine clearance of 20 to 49 ml/minute, give 750 mg P.O. or I.V. every 48 hours; for creatinine clearance of 10 to 19 ml/minute and for patients on peritoneal dialysis or hemodialysis, give 750 mg initial dose P.O. or I.V., and then 500 mg every 48 hours.

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