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Benzodiazepines and barbiturates

Geriatric patients are at risk for many dosage-related effects of benzodiazepines. Rare idiosyncratic reactions that occur primarily in these patients include nervousness, restlessness, talkativeness, apprehension, euphoria, and excitement.
   Use of barbiturates for their hypnotic effects may be dangerous for the elderly. After hypnotic dosages, the hangover effect commonly occurs, accompanied by impairment of judgment and motor skills that can last for many hours and may lead to falls. When hypnotic dosages are discontinued, elderly patients may experience a change in sleep patterns. These patients may exhibit excitement and confusion, particularly when taking short-acting compounds such as secobarbital.
     
   

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